PMID: 16352683
Peptide Research
CJC 1295 + Ipamorelin
SKU: CP10
This blend pairs two distinct GH-releasing mechanisms. CJC-1295 is a GHRH analog that binds GHRH receptors on pituitary somatotrophs (4-fold greater receptor affinity than native GHRH). Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist acting through a separate pathway…
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Mechanism of Action
This blend pairs two distinct GH-releasing mechanisms. CJC-1295 is a GHRH analog that binds GHRH receptors on pituitary somatotrophs (4-fold greater receptor affinity than native GHRH). Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist acting through a separate pathway. Co-administration produces synergistic pulsatile GH release while Ipamorelin's selectivity avoids cortisol, prolactin, and aldosterone elevation typical of earlier secretagogues.
Research Studies
2 peer-reviewed studies curated for CJC 1295 + Ipamorelin.
Related Research
Often compared with standalone Ipamorelin and Tesamorelin in GH-axis research. Paired with IGF-1 LR3 for downstream anabolic pathway studies, and with recovery peptides like Wolverine or GLOW in tissue repair protocols.